Research article about virus sample preparation on the Cover of Analyst
Back-Cover of Analyst

Research article about virus sample preparation on the Cover of Analyst

Research article of the Laboratory for Sensors on the back cover of the new Analyst issue: A lab-on-a-chip for free-flow electrophoretic preconcentration of viruses and gel electrophoretic DNA extraction

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Back-Cover of Analyst

In this work, we demonstrate the complete microfluidic preparation of amplifiable virus DNA from dilute specimens on a single device. For the first time, free-flow electrophoresis is used to concentrate the viral sample followed by thermal lysis and gel electrophoretic nucleic acid extraction. The small size of the chip, the user-friendly operation with low risk of cross-contamination and the high potential for automation, makes it an ideal candidate in the field of point-of-care diagnostics.

Link: Matthias Hügle, Ole Behrmann, Madlen Raum, Frank T. Hufert, Gerald A. Urban, Gregory Dame. A lab-on-a-chip for free-flow electrophoretic preconcentration of viruses and gel electrophoretic DNA extraction, Analyst, 2020, 145, 2554 - 2561, doi.org/10.1039/C9AN02333J

Contact:
Matthias Hügle
Laboratory for Sensors
IMTEK - Department of Microsystems Engineering
Phone: 0761/203-7267
huegle(at)imtek.de

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