Review Paper: In Vivo Biosensors
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The article summarizes and critically evaluates the state of the art in electrochemical biosensors for in vivo applications. Special focus lies on current microfabrication technologies for such sensor platforms and a unique, comprehensive comparison of the performance of enzymatic in vivo sensors.
Beyond the measurement of blood glucose, such glutamate or lactate sensors are used for the fast and precise in situ measurement of energy and neurotransmitter metabolism in various biomedical fields, particularly in the neurosciences. That includes the research on the causes and therapy of neurodegenerative diseases, cancer or stroke.
The open access article is available free of charge:
A. Weltin, J. Kieninger, G. A. Urban: “Microfabricated, amperometric, enzyme-based biosensors for in vivo applications”, Analytical and Bioanalytical Chemistry, 2016. DOI: 10.1007/s00216-016-9420-4.
Dr.-Ing. Andreas Weltin
Laboratory for Sensors
Phone: 0761/203-7263
E-mail: weltin@imtek.de
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